diff --git a/.github/workflows/pythonapp.yml b/.github/workflows/pythonapp.yml
index 5fdec1e11e..8bbf155beb 100644
--- a/.github/workflows/pythonapp.yml
+++ b/.github/workflows/pythonapp.yml
@@ -91,8 +91,8 @@ jobs:
       shell: bash
     - name: Run compiled (${{ runner.os }})
       run: |
-        python setup.py develop --uninstall
-        BUILD_MONAI=1 python setup.py develop  # compile the cpp extensions
+        python -m pip uninstall -y monai
+        BUILD_MONAI=1 python -m pip install -e .  # compile the cpp extensions
       shell: bash
     - name: Run quick tests (CPU ${{ runner.os }})
       run: |
diff --git a/docs/source/installation.md b/docs/source/installation.md
index b8befc10b4..646b34a23f 100644
--- a/docs/source/installation.md
+++ b/docs/source/installation.md
@@ -135,23 +135,23 @@ You can install it by running:
 
 ```bash
 cd MONAI/
-python setup.py develop
+pip install -e .
 ```
 
 or, to build with MONAI C++/CUDA extensions and install:
 
 ```bash
 cd MONAI/
-BUILD_MONAI=1 python setup.py develop
+BUILD_MONAI=1 pip install -e .
 # for MacOS
-BUILD_MONAI=1 CC=clang CXX=clang++ python setup.py develop
+BUILD_MONAI=1 CC=clang CXX=clang++ pip install -e .
 ```
 
 To uninstall the package please run:
 
 ```bash
 cd MONAI/
-python setup.py develop --uninstall
+pip uninstall -y monai
 
 # to further clean up the MONAI/ folder (Bash script)
 ./runtests.sh --clean
diff --git a/requirements-min.txt b/requirements-min.txt
index afc1bf6e07..21cf9d5e5c 100644
--- a/requirements-min.txt
+++ b/requirements-min.txt
@@ -1,7 +1,7 @@
 # Requirements for minimal tests
 -r requirements.txt
 setuptools>=50.3.0,<66.0.0,!=60.6.0 ; python_version < "3.12"
-setuptools>=70.2.0,<=79.0.1; python_version >= "3.12"
+setuptools>=70.2.0; python_version >= "3.12"
 coverage>=5.5
 parameterized
 packaging
diff --git a/runtests.sh b/runtests.sh
index 18cb0ab73a..ccf6400a7a 100755
--- a/runtests.sh
+++ b/runtests.sh
@@ -73,7 +73,7 @@ function print_usage {
     echo "./runtests.sh -f                      # run coding style and static type checking."
     echo "./runtests.sh --quick --unittests     # run minimal unit tests, for quick verification during code developments."
     echo "./runtests.sh --autofix               # run automatic code formatting using \"isort\" and \"black\"."
-    echo "./runtests.sh --clean                 # clean up temporary files and run \"${PY_EXE} setup.py develop --uninstall\"."
+    echo "./runtests.sh --clean                 # clean up temporary files and uninstall MONAI development package."
     echo "./runtests.sh --formatfix -p /my/code # run automatic code formatting using \"isort\" and \"black\" in specified path."
     echo ""
     echo "Code style check options:"
@@ -143,12 +143,12 @@ function compile_cpp {
     echo "Compiling and installing MONAI cpp extensions..."
     # depends on setup.py behaviour for building
     # currently setup.py uses environment variables: BUILD_MONAI and FORCE_CUDA
-    ${cmdPrefix}"${PY_EXE}" setup.py develop --user --uninstall
+    ${cmdPrefix}"${PY_EXE}" -m pip uninstall -y monai
     if [[ "$OSTYPE" == "darwin"* ]];
     then  # clang for mac os
-        CC=clang CXX=clang++ ${cmdPrefix}"${PY_EXE}" setup.py develop --user
+        BUILD_MONAI=1 CC=clang CXX=clang++ ${cmdPrefix}"${PY_EXE}" -m pip install -e .
     else
-        ${cmdPrefix}"${PY_EXE}" setup.py develop --user
+        BUILD_MONAI=1 ${cmdPrefix}"${PY_EXE}" -m pip install -e .
     fi
 }
 
@@ -179,7 +179,7 @@ function clean_py {
 
     # uninstall the development package
     echo "Uninstalling MONAI development files..."
-    ${cmdPrefix}"${PY_EXE}" setup.py develop --user --uninstall
+    ${cmdPrefix}"${PY_EXE}" -m pip uninstall -y monai
 
     # remove temporary files (in the directory of this script)
     TO_CLEAN="$( cd "$( dirname "${BASH_SOURCE[0]}" )" >/dev/null 2>&1 && pwd )"